Any Molecules into

Any Cells by

Any Users

Hydroporator®

is MxT Biotech’s patented non-viral microfluidic gene delivery platform,
driving a paradigm shift in genome editing and cell & gene therapy
through its highly effective gene delivery performance.

Technology

How Hydroporator® works

Hydroporator® fluidically stretches individual cells to instantaneously permeabilize their cell and nuclear membranes, enabling the rapid delivery of biomolecules. This unique method allows for highly efficient delivery while maintaining the viability and cell functionality.
  • 01

    The sample (cells + delivery cargos) is infused into the Hydroporator and flows through the microfluidic cartridge.

    SAMPLE LOADING
    SAMPLE LOADING
  • 02

    The cells are fluidically deformed by the microfluidic vortex, creating nanopores in their cell and nuclear membranes.

    FLUIDIC CELL DEFORMATION
    FLUIDIC CELL DEFORMATION
  • 03

    As the cells recover their shape, nearby delivery cargos enter through the nanopores via convection and diffusion.

    DELIVERY
    DELIVERY
  • 04

    As the perforated membrane reseals within a minute, health cells with delivered cargos are recovered.

    MEMBRANE RESEALING
    MEMBRANE RESEALING
Applications

What Hydroporator® can offer

Hydroporator® revolutionizes gene delivery with its cost-effective, scalable, and efficient performance, ensuring high cell viability even in challenging primary cell applications. Hydroporator® accelerates breakthroughs in both research and production.

Discover more insights in our publications!

Explore Our Publications
Advantages

Why Hydroporator®?

  • Methods
  • Delivery Efficiency
  • Cell stability /Functionality
  • Throughput
  • Large Plasmid Delivery
  • Large Nanoparticle Delivery
  • Cost
  • Electroporation
  • $$
  • Lipid nanoparticle
  • $$
  • Viral transduction
  • $$$$
  • Hydroporator®
  • $
Resource:   ACS Nano (1) (2020), ACS Nano (2) (2020), Advanced Science (2021), Nano Letters (2023), Lab on a Chip (2024)
  • Genome Editing
    Genome Editing
    Cell Engineering
    Cell Engineering
  • Cell Therapy
    Cell Therapy
    Cell Line Development
    Cell Line Development
  • Gene Therapy
    Gene Therapy
    Immunology
    Immunology
  • Regenerative Medicine
    Regenerative Medicine
    Cell Biologoy
    Cell Biologoy
Applications

Who Hydroporator® can offer

Hydroporator® is designed to support researchers and industries at the forefront of next-generation biotechnology, including cell & gene therapy and genome editing. This cutting-edge technology drives breakthroughs in your research by enhancing research outcomes.

Explore how it can transform your work with our application notes.

Application Note
Partnership

Where to Begin Your Research with Hydroporator®

Join our VIP (Validation of Instrumentation Program) for tailored collaboration and dedicated technical support. Through this program, we work closely to validate and optimize Hydroporator® to meet your specific needs in research and production. Discover how our partnership can elevate your projects and drive success.

Become our VIP!